报告人： 薛人望 教授

报告题目：Evolution and Darwinian medicine 演化論与达爾文医学

邀请人：史庆华  教授

报告地点：2021.3.29 晚19：00   429会议室

       个人简介：

       Aaron Hsueh (Professor, Department of Obstetrics and Gynecology, Stanford University School of Medicine) is an ovarian physiologist and has published in the field for decades with >390 refereed papers.  His lab has investigated the hormonal regulation of granulosa cell functions, leading to the establishment of a sensitive in vitro FSH bioassay and the application of a long-acting FSH analog (ELONVA) now in clinical use. His lab also contributed to the understanding of ovarian follicle growth and atresia, intraovarian mechanisms of oocyte maturation, and autocrine/paracrine regulation of early embryonic development.  His lab cloned human FSH and LH receptors together with five related receptors (named them as LGR4-8) before identifying LGR7 as the relaxin receptor.  The Hsueh lab established and maintained the Ovarian Kaleidoscope Database (OKdb, http://okdb.appliedbioinfo.net/4_search.html) over 20 years as an online resource for ovarian researchers to search for ovarian literature and DNA microarray data, together with Human Plasma Membrane Receptome (HPMR: http://www.receptome.org/), listing all human plasma membrane receptors linked to their cognate ligands.  In 2013, his lab established an in vitro activation (IVA) method to activate ovarian preantral follicles for the derivation of mature oocytes in patients with primary ovarian insufficiency and low ovarian reserve.

报告人： 薛人望 教授

报告题目：Ovarian kaleidoscope database and genes responsible for POI ，PCOS and         ovarian senescence 卵巢万花筒数据库以及影响POI , PCOS，卵巢衰老的基因

邀请人：史庆华  教授

报告地点：2021.3.30  上午9：00    429会议室

       个人简介：

       Aaron Hsueh (Professor, Department of Obstetrics and Gynecology, Stanford University School of Medicine) is an ovarian physiologist and has published in the field for decades with >390 refereed papers.  His lab has investigated the hormonal regulation of granulosa cell functions, leading to the establishment of a sensitive in vitro FSH bioassay and the application of a long-acting FSH analog (ELONVA) now in clinical use. His lab also contributed to the understanding of ovarian follicle growth and atresia, intraovarian mechanisms of oocyte maturation, and autocrine/paracrine regulation of early embryonic development.  His lab cloned human FSH and LH receptors together with five related receptors (named them as LGR4-8) before identifying LGR7 as the relaxin receptor.  The Hsueh lab established and maintained the Ovarian Kaleidoscope Database (OKdb, http://okdb.appliedbioinfo.net/4_search.html) over 20 years as an online resource for ovarian researchers to search for ovarian literature and DNA microarray data, together with Human Plasma Membrane Receptome (HPMR: http://www.receptome.org/), listing all human plasma membrane receptors linked to their cognate ligands.  In 2013, his lab established an in vitro activation (IVA) method to activate ovarian preantral follicles for the derivation of mature oocytes in patients with primary ovarian insufficiency and low ovarian reserve.