方芳，中国科学技术大学副研究员，2012年至今于中国科学技术大学从事博士后、副研究员工作。先后荣获国际肿瘤免疫治疗协会国际学者奖，长三角生物工程协会优秀青年学者。2019年被聘任为中国生物医学工程学会免疫治疗工程分会第一届青年委员。主持国家自然基金面上项目、青年基金及安徽省自然基金；参与新药创制、传染病重大专项，自然创新群体、973、安徽省重大研究专项等科研项目。相关成果发表在International Journal of Cancer, Cell death and disease, Frontiers in Immunology等学术期刊。

主要研究兴趣：

天然和获得性免疫在肿瘤发生发展中的作用和机制，以及抗肿瘤免疫技术和产品的开发应用。

代表性论文：

1.  Yuhui Miao, Ming Jiang, Lu Qi, De Yang, Weihua Xiao* and Fang Fang*. BCAP Regulates Dendritic Cell Maturation Through the Dual-Regulation of NF-κB and PI3K/AKT Signaling During Infection, Front. Immunol., 2020 Feb; 11:250.

2.  Huimin Liu, Siqi Xie, Fang Fang*, Dhananjaya V. Kalvakolanu* and Weihua Xiao* . SHQ1 is an ER stress response gene that facilitates chemotherapeutics-induced apoptosis via sensitizing ER-stress response, Cell Death and Disease, 2020; 11:445.

3.  Lu Qi , Qiuyan Zhang, Yuhui Miao, Wenyao Kang, Zhigang Tian, Damo Xu, Weihua Xiao*, Fang Fang*. Interleukin-33 Activates and Recruits Natural Killer Cells to Inhibit Pulmonary Metastatic Cancer Development, International journal of Cancer,2019 Nov; 146, 1421–1434.

4.  Fang Fang, Wei Wang, Minhua Chen, Zhigang Tian*, Weihua Xiao*. Cancer Biol Med, 2019, 16(4), 647-654.

5.  Fang F, Xiao W*, Tian Z*. Challenges of NK cell-based immunotherapy in the new era , Frontiers of Medicine, 2018.8, 12(4): 440~450

6.  Fang F, Xiao W*, Tian Z*. NK cell-based immunotherapy for cancer. Semin Immunol. 2017.06, 31: 37~54.

7.  Li R, Fang F*, Jiang M, Wang C, Ma J, Kang W, Zhang Q, Miao Y, Wang D, Guo Y, Zhang L, Guo Y, Zhao H, Yang, Tian Z, Xiao W*. STAT3 and NF-κB are Simultaneously Suppressed in Dendritic Cells in Lung Cancer. Sci Rep. 2017 Mar 28;7:45395.

8.  Fang, F.#, Y. Wang#, R. Li, Y. Zhao, Y. Guo, M. Jiang, J. Sun, Y. Ma, Z. J. Ren, Z. G. Tian, F. Wei, D. Yang, and W. H. Xiao. 2010. Transcription Factor E2F1 Suppresses Dendritic Cell Maturation. J. Immunol. 184: 6084-6091.

联系方式：

合肥市黄山路443号中国科学技术大学生命学院免疫所
Tel: 0551-63600535
Fax: 0551-63600535
E-mail: fangfang@mail.ustc.edu.cn